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FACULTATEA DE BIOLOGIE / UNIVERSITATEA DIN BUCUREȘTI (FB-UB)



I. Departamentul de Investigație Moleculară

A. Grupul de cercetare "Biocompatibilitate și Inginerie Tisulară”

Conducătorul grupului de cercetare: Dr. Anișoara CÎMPEAN

Articole publicate în reviste indexate ISI (selecție):

  1. Rusen, L.; Brajnicov, S.; Neacsu, P.; Marascu, V.; Bonciu, A.; Dinescu, M.; Dinca, V.; Cimpean, A.; 2017. Novel degradable biointerfacing nanocomposite coatings for modulating the osteoblast response. SURFACE & COATINGS TECHNOLOGY, 325, 397-409;
  2. Tirca, I.; Mitran, V.; Marascu, V.; Ion, V.; Brajnicov, S.; Stokker-Cheregi, F.; Popovici, I.A.; Cimpean, A.; Dinca, V.; Dinescu, M.; 2017. In vitro testing of curcumin based composites coatings as antitumoral systems against osteosarcoma cells. APPLIED SURFACE SCIENCE, 425, 1040-1051;
  3. Miculescu, F.; Mocanu, A.C.; Stan, G.E.; Miculescu, M.; Maidaniuc, A.; Cimpean, A.; Mitran, V.; Voicu, S.I.; Machedon-Pisu, T.; Ciocan, L.T.; 2017. Influence of the modulated two-step synthesis of biogenic hydroxyapatite on biomimetic products’ surface. APPLIED SURFACE SCIENCE, In Press, Corrected Proof;
  4. Tihan, G.T.; Sereanu, V.; Meghea, A.; Voicu, G.; Albu, M.G.; Mitran, V.; Cimpean, A.; Zgarian, R.G.; 2017. Innovative methodology for developing a bone grafting composite biomaterial starting from the seashell of Rapana thomasiana. COMPTES RENDUS CHIMIE, 20, 440-445;
  5. Neacsu, P.; Staras A.I.; Voicu, S.I.; Ionascu, I.; Soare, T.; Uzun, S.; Cojocaru V.D.; Pandele, A.M.; Croitoru, S.M.; Miculescu, F.; Cotrut, C.M.; Dan, I.; Cimpean, A.; 2017. Characterization and in vitro and in vivo assessment of a novel cellulose acetate-coated Mg-based alloy for orthopedic applications. MATERIALS, 10 (7), 686;
  6. Ion, R.; Drob, S.I.; Ijaz, M.F.; Vasilescu, C.; Osiceanu, P.; Gordin, D.-M.; Cimpean, A.; Gloriant, T.; 2016. Surface characterization, corrosion resistance and in vitro biocompatibility of a new Ti‐Hf‐Mo‐Sn alloy. MATERIALS, 9 (10), 818;
  7. Ion, R.; Luculescu, C.; Cimpean, A.; Marx, P.; Gordin, D.-M.; Gloriant, T.; 2016. Nitride coating enhances endothelialization on biomedical NiTi shape memory alloy. MATERIALS SCIENCE AND ENGINEERING C, 62, 686–691;
  8. Rusen, L.; Neacsu, P.; Cimpean, A.; Valentin, I.; Brajnicov, S.; Dumitrescu, L.N.; Banita, J.; Dinca, V.; Dinescu, M.; 2015. In vitro evaluation of poly(ethylene glycol)-block-poly(ε)-caprolactone) methyl ether copolymer coating effects on cells adhesion and proliferation. APPLIED SURFACE SCIENCE, 374, 23-30;
  9. Voicu, S.I.; Condruz, R.M.; Mitran, V.; Cimpean, A.; Miculescu, F.; Andronescu, C.; Miculescu, M.; Thakur, V.K.; 2016. Sericin covalent immobilization onto cellulose acetate membrane for potential osseointegration applications. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 4, 1765-1774;
  10. Ion, R.; Vizireanu, S.; Luculescu, C.; Cimpean, A.; Dinescu, G.; 2016. Vertically, interconnected graphene carbon nanowalls as biocompatible scaffolds for osteoblast cells. JOURNAL OF PHYSICS D: APPLIED PHYSICS, 49 (27): 274004;
  11. Neacsu, P.; Mazare, A.; Schmuki, P.; Cimpean A.; 2015. Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways. INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 6455–6467;
  12. Mitran, V.; Vasilescu, C.; Drob, S.I.; Osiceanu, P.; Calderon-Moreno, J.M.; Tabirca, M.-C.; Gordin, D.-M.; Gloriant, T.; Cimpean A.; 2015. Biological behaviour and enhanced anticorrosive performance of the nitrided superelastic Ti-23Nb-0.7Ta-2Zr-0.5N alloy. BIOMED RESEARCH INTERNATIONAL, 215: 261802;
  13. Ion, R.; Vizireanu, S.; Stancu, C.E.; Luculescu, C.; Cimpean, A.; Dinescu, G.; 2015. Surface plasma functionalization influences macrophage behavior on carbon nanowalls. MATERIALS SCIENCE AND ENGINEERING C, 48, 118-125;
  14. Mitran, V.; Albu, M.G.; Vasile, E.; Cimpean, A.; Costache, M.; 2015. Dose-related effects of sericin on preadipocyte behavior within collagen/sericin hybrid scaffolds. PROGRESS IN NATURAL SCIENCE: MATERIALS INTERNATIONAL, 25, 122-130;
  15. Neacsu, P.; Gordin, D.-M.; Mitran, V.; Gloriant, T.; Costache, M.; Cimpean, A.; 2015. In vitro performance assessment of new beta Ti–Mo–Nb alloy compositions. MATERIALS SCIENCE AND ENGINEERING C, 47, 105-113;
  16. Ion, R.; Stoian, A.B.; Dumitriu, C.; Grigorescu, S.; Mazare, A.; Cimpean, A.; Demetrescu, I.; Schmuki, P.; 2015. Nanochannels formed on TiZr alloy improve biological response. ACTA BIOMATERIALIA, 24, 370-377;
  17. Drob, S.I.; Vasilescu, C.; Calderon Moreno, J.M.; Osiceanu, P.; Neacsu, P.; Cimpean, A.; Gordin, D.M.; Gloriant, T.; 2015. Multifunctional “gum metal” titanium-based alloy: Its long-term electrochemical behavior and macrophage response. INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 10, 10738-10755;
  18. Corobea, M.S.; Albu, M.G.; Ion, R.; Cimpean, A.; Miculescu, F.; Antoniac, I.V.; Raditoiu, V.; Sirbu, I.; Stoenescu, M.; Voicu, S.I.; Ghica, M.V.; 2015. Modification of titanium surface with collagen and doxycycline as a new approach in dental implants. JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY, 29, 2537-2550;
  19. Neacsu, P.; Mazare, A.; Cimpean, A.; Park, J.; Costache, M.; Schmuki, P.; Demetrescu, I.; 2014. Reduced inflammatory activity of RAW 264.7 macrophages on titania nanotube modified Ti surface. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 55, 187-195;
  20. Cimpean, A.; Vasilescu, E.; Drob, P.; Cinca, I.; Vasilescu, C.; Anastasescu, M.; Mitran, V.; Drob, S.I.; 2014. Enhancement of the electrochemical behaviour and biological performance of Ti–25Ta–5Zr alloy by thermo-mechanical processing. MATERIALS SCIENCE AND ENGINEERING C, 38, 127-142;
  21. Ion, R.; Gordin, D.M.; Mitran, V.; Osiceanu, P.; Dinescu, S.; Gloriant, T.; Cimpean, A.; 2014. In vitro bio-functional performances of the novel superelastic beta-type Ti–23Nb–0.7Ta–2Zr–0.5N alloy. MATERIALS SCIENCE AND ENGINEERING C, 35, 411-419;
  22. Gordin, D.M.; Ion, R.; Vasilescu, C.; Drob, S.I.; Cimpean, A.; Gloriant, T.; 2014. Potentiality of the “Gum Metal” titanium-based alloy composition for biomedical applications. MATERIALS SCIENCE AND ENGINEERING C, 44, 362-370;
  23. Ion, R.; Vasilescu, C.; Drob, P.; Vasilescu, E.; Cimpean, A.; Drob, I.; Gordin, D.M.; Gloriant, T.; 2014. Long-term corrosion performances and cytocompatibility of nitrided Ti and Ti–6Al–4V alloy in severe functional conditions. MATERIALS AND CORROSION, 65, 593-604;
  24. Gordin, D.M.; Busardo, D.; Cimpean, A.; Vasilescu, C.; Höche, D.; Drob, S.I.; Mitran, V.; Cornen, M.; Gloriant, T.; 2013. Design of a nitrogen-implanted titanium-based superelastic alloy with optimized properties for biomedical applications. MATERIALS SCIENCE AND ENGINEERING C, 33, 4173-4182;
  25. Andronescu, E.; Ficai, A.; Albu, M.; Mitran, V.; Sonmez, M.; Ficai, D.; Ion, R.; Cimpean, A.; 2013. Collagen-hydroxyapatite/cisplatin drug delivery systems for locoregional treatment of bone cancer. TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 12, 275-284;
  26. Mindroiu, M.; Ion, R.; Pirvu, C.; Cimpean, A.; 2013. Surfactant-dependent macrophage response to polypyrrole-based coatings electrodeposited on Ti6Al7Nb alloy. MATERIALS SCIENCE AND ENGINEERING C, 33, 3353–3361;
  27. Dimonie, D.; Petrache, M.; Gabor, R.; Trandafir, I.; Nicolae, C.; Dimonie, M.; Cimpean, A.; Galateanu, B.; Vasile, E.; Trusca, R.; Jinescu, G.; 2013. Parameters influencing the properties of layered shaped ionotropic alginate hydrogels designed for soft tissue engineering. DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, 8, 1727-1738;
  28. Dinescu, S.; Galateanu, B.; Albu, M.; Cimpean, A.; Dinischiotu, A.; Costache, M.; 2013. Sericin enhances the bioperformance of collagen-based matrices preseeded with human-adipose derived stem cells (hADSCs). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14, 1870-1889;
  29. Galateanu, B.; Dinescu, S.; Cimpean, A.; Dinischiotu, A.; Costache, M.; 2012. Modulation of adipogenic conditions for prospective use of hADSCs in adipose tissue engineering. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 13, 15881-15900;
  30. Mindroiu, M.; Pirvu, C.; Cimpean, A.; Demetrescu, I.; 2012. Corrosion and biocompatibility of PPy/PEG coating electrodeposited on Ti6Al7Nb alloy. MATERIALS AND CORROSION, 64 (10), 926-931
  31. Galateanu, B.; Dimonie, D.; Vasile, E.; Nae, S.; Cimpean, A.; Costache, M.; 2012. Layer-shaped alginate hydrogels enhance the biological performance of human adipose- derived stem cells. BMC BIOTECHNOLOGY, 12: 35;
  32. Cimpean, A.; Mitran, V.; Ciofrangeanu, C.M.; Galateanu, B.; Bertrand, E.; Gordin, D.-M.; Iordachescu, D.; Gloriant, T.; 2012. Osteoblast cell behavior on the new beta-type Ti–25Ta–25Nb alloy. MATERIALS SCIENCE AND ENGINEERING C, 32, 1554–1563;
  33. Gordin, D.M.; Gloriant, T.; Chane-Pane, V.; Busardo, D.; Mitran, V.; Hoche, D.; Vasilescu, C.; Drob, S.I.; Cimpean, A.; 2012. Surface characterization and biocompatibility of titanium alloys implanted with nitrogen by Hardion+ technology. JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE, 23, 2953-2966;
  34. Cimpean, A.; Popescu, S.; Ciofrangeanu, C.M.; Gleizes, A.N.; 2011. Effects of LP-MOCVD prepared TiO2 thin films on the in vitro behavior of gingival fibroblasts. MATERIALS CHEMISTRY AND PHYSICS, 125, 485-492;
  35. Vasilescu, C.; Calderon Moreno, J.M.; Cimpean, A.; Cojocaru, D.; Cinca, I.; Andronescu, E.; Grigore, F.; Galateanu, B.; Drob, S.I.; 2011. Synthesis, mechanical and structural properties and biological activity of some nanostructured bone scaffolds. DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES, 6, 523-534.

Cărți / capitole de carte (selecție):

  1. Cimpean, A.; Ion, R.; Ciofrangeanu, C.; Mitran, V.; Galateanu, B.; Iordachescu, D.; 2008. Ghid practic de cercetare in vitro a biocompatibilității materialelor dentare, Ed. Ars Docendi, ISBN: 978-973-558-364-4;
  2. Iordachescu, D.; Cimpean, A.; Stan, C.; 2004. Modelarea matricei extracelulare. Aplicații în ingineria tisulară, Ed. Pro-Transilvania, ISBN 973-715-024-4;
  3. Miculescu, F.; Maidaniuc, A.; Stan, G.E.; Miculescu, M.; Voicu, S.I.; Cimpean, A.; Mitran, V.; Batalu, D.; 2016. Tuning hydroxyapatite particles’ characteristics for solid free form fabrication of bone scaffolds, Chapter 7 in Advanced Composite Materials, Tiwari, A.; Alenezi, M.R.; Jun, S.C. (Eds), Scrivener Publishing LLC, 321-398, ISBN: 9781119242536;
  4. Dimonie, D.; Petrache, M.; Doncea, S.; Gabor, R.; Vasile, E.; Cimpean, A.; Fierascu, R.C.; Cristian, N.; Dinescu, S.; Trandafir, I.; Anton, L.; Fierascu, I.; Galateanu, B.; 2013. New approaches to develop 3D layer shaped scaffolds for soft tissue engineering, in: Advanced biocompatible structures for prospective bioengineering: Concepts and strategies, The Publishing House of the Romanian Academy, 74-124, ISBN: 978-973-27-2317-3
  5. Cimpean, A.; Ion, R.; Gordin, D.-M.; Neacsu, P.; Mitran, V.; Gloriant, T.; 2013. Biomaterials as modulators of macrophage inflammatory response, in Nanotechnology – Vol. 11: Biomaterials, Govil, J.N. (Ed.), Studium Press LLC, 139-176.

Brevete de invenție (selecție):

  1. Calderon Moreno, J.M.; Popa, M.; Vasilescu, C.; Drob, S.I.; Cimpean, A.; Mitran, V.; A/00055/26.01.2016. Procedura sonochimica pentru nanoacoperire antibacteriana aplicata pe suprafata unui nou aliaj ternar de titan cu aplicatie in implantologia ortopedica;
  2. Dimonie, D.; Trandafir, I.; Nicolae, C.; Gabor, R.; Constantin, V.; Petrache, M.; Cimpean, A.; Galateanu, B.; Costache, M.; RO128708 (A2), A/01263/29.11.2011. Compoziție și procedeu pentru obținerea unor hidrogeluri destinate regenerării țesutului adipos, OSIM (BOPI nr. 8/2013).

Proiecte internaționale (selecție):

  1. ERA-NET MANUNET 28 / 2017-2019. Implanturi din aliaj biodegradabil de magneziu, cu nanoacoperiri bioactive, degradare controlată și oseointegrare îmbunătățită;
  2. ERA-NET MANUNET 31 /2017-2019. Implanturi dentare avansate din aliaj de Ti beta cu biocompatibilitate ridicată și suprafață funcționalizată;
  3. 20_RO-FR / 2014-2016. BIOcompatible Medical IMplants Elaborated from nitrided TItanium-based Superelastic alloys / Implanturi medicale biocompatibile elaborate din aliaje superelastice, pe bază de titan, nitrurate (BIOMIMETIS);
  4. ERA-NET MNT 7-017.3 / 2009-2011. Advanced nanostructured metallic biomaterials for implantable medical devices / Biomateriale metalice avansate, nanostructurate, pentru implante ortopedice (NanoBioAll).

Proiecte naționale (selecție):

  1. IDEI 55 / 2017-2021. Nanotuburi de TiO2 spațiate utilizate ca platforme pentru eliberare de medicamente și regenerare osoasă;
  2. PED 97 / 2017-2018. Design innovator al suprafeței pentru prelungirea perioadei de utilizarea și a siguranței implanturilor dentare și ortopedice;
  3. PED 108 / 2017-2018. O nouă tehnologie pentru sinteza și fabricarea implanturilor biomimetice derivate din surse biogene utilizate pentru chirurgia reconstructivă osoasă;
  4. PED 127 / 2017-2018. Structuri poroase biomimetice obținute prin printare 3D pentru ingineria țesutului osos;
  5. PED 149 / 2017-2018. Îmbunătățrea reparării defectelor osoase de către nanostructuri pe bază de TiO2 inspirate de la scoică și funcționalizate cu fitomolecule bioactive;
  6. PCCA 195 / 2014-2016. Strategii terapeutice pentru îmbunatățirea răspunsului de vindecare a osului prin utilizarea de implanturi pe bază de magneziu bioresorbabile cu acoperiri bioactive;
  7. PCCA 213 / 2014-2016. Implanturi ortopedice obtinute din aliaje multifunctionale tip "Gum";
  8. PCCA 239 / 2014-2016. Nouă generație de implanturi ortopedice bazate pe noi bioaliaje de Ti cu invelișuri biomimetice hibride;
  9. PCCA 253 / 2014-2016. Noi acoperiri nanostructurate multifuncționale pentru implanturi ortopedice;
  10. IDEI 188 / 2011-2015. Efecte in vitro ale aliajelor de beta titan asupra comportamentului biologic al macrofagelor și interacțiilor lor cu osteoblastele;
  11. C 72-198 / 2008-2011. Nanobiocompozite multifuncționale utilizate ca suporturi regenerative și medicamentoase (SIMAC);
  12. C 71-021 / 2007-2010. Noi biomateriale avansate, nanostructurate cu bază de titan și elemente de aliere netoxice (BIOTITANANO);
  13. C 41-059 / 2007-2010. Interacții bio / non-bio implicate în design-ul țesuturilor tari;
  14. CNCSIS A 1019 / 2006-2008. Studii complexe privind interacția fibroblastelor gingivale cu materialele dentare în vederea dezvoltării unor standarde de evaluare biologică;
  15. CEEX-2 VIASAN 77 / 2006-2008. Studii la nivel celular și molecular privind activitățile biologice ale curcuminei în vederea evaluării potențialului terapeutic;
  16. CEEX-1 AMCSIT 40 / 2005-2007. Materiale nanostructurate biocompatibile pentru dispozitive medicale;
  17. RELANSIN 1955 / 2004-2006. Nanostructuri bioactive din hidroxiapatită depusă chimic din soluții similare plasmei sanguine pe implanturi de titan;
  18. VIASAN 467 / 2004-2006. Studiu la nivel celular și molecular privind acțiunea agenților terapeutici în psoriasis.

II. Departmenntul de biotehnologie și resurse regenerabile

Conducătorul grupului de cercetare: Dr. Mariana CHIFIRIUC

Articole publicate în reviste indexate ISI (selecție):

  1. Visan, A.; Cristescu, R.; Stefan, N.; Miroiu, M.; Nita, C.; Socol, M.; Florica, C.; Rasoga, O.; Zgura, I.; Sima, L.E.; Chiritoiu, M.; Chifiriuc, M.C.; Holban, A.M.; Mihailescu, I.N.; Socol, G.; 2017. Antimicrobial polycaprolactone/polyethylene glycol embedded lysozyme coatings of Ti implants for osteoblast functional properties in tissue engineering. APPLIED SURFACE SCIENCE, 417, 234–243;
  2. Al Tameemi, M.B.M.; Stan, R.; Prisacari, V.; Voicu; G.; Popa, M.; Chifiriuc, M.C.; Ott, C.; Marton, G.; Meghea, A.; 2017. Antimicrobial performance of nanostructured silica-titania sieves loaded with izohidrafural against microbial strains isolated from urinary tract infections. COMPTES RENDUS CHIMIE, 20, 475-483;
  3. Tudose, M.; Culita, D.C.; Musuc, A.M.; Marinescu, G.; Somacescu, S.; Munteanu, C.; Bleotu, C.; Chifiriuc, M.C.; 2016. Multifunctional silver nanoparticles-decorated silica functionalized with retinoic acid with anti-proliferative and antimicrobial properties. JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 26, 1043-1052;
  4. Stoica, A.O.; Andronescu, E.; Ghitulica, C.D.; Voicu, G.; Grumezescu, A.M.; Popa, M.; Chifiriuc, M.C.; 2016. Preparation and characterization of undoped and cobalt doped ZnO for antimicrobial use. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 510, 430-438;
  5. Chifiriuc, M.C.; Ratiu, A.C.; Popa, M.; Ecovoiu, A.A.; 2016. Drosophotoxicology: An emerging research area for assessing nanoparticles interaction with living organisms. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17, 1-14;
  6. Ciubuca, B.M.; Saviuc, C.M.; Chifiriuc, M.C.; Lazar, V.; 2016. Microbial resistance to natural compounds: Challenges for developing novel alternatives to antibiotics. CURRENT ORGANIC CHEMISTRY, 20, 2983-2988;
  7. Gingasu, D.; Mindru, I.; Mocioiu, O.C.; Preda, S.; Stanica, N.; Patron, L.; Ianculescu, A.; Oprea, O.; Nita, S.; Paraschiv, I.; Popa, M.; Saviuc, C.; Bleotu, C.; Chifiriuc, M.C.; 2016. Synthesis of nanocrystalline cobalt ferrite through soft chemistry methods: A green chemistry approach using sesame seed extract. MATERIALS CHEMISTRY AND PHYSICS, 182, 219-230;
  8. Lungu, M.V.; Vasile, E.; Lucaci, M.; Patroi, D.; Mihailescu, N.; Grigore, F.; Marinescu, V.; Bratulescu, A.; Mitrea, S.; Sobetkii, A.; Sobetkii, A.A.; Popa, M.; Chifiriuc, M.C.; 2016. Investigation of optical, structural, morphological and antimicrobial properties of carboxymethyl cellulose capped Ag-ZnO nanocomposites prepared by chemical and mechanical methods. MATERIALS CHARACTERIZATION, 120, 69-81;
  9. Saviuc, C.; Gheorghe, I.; Coban, S.; Drumea, V.; Chifiriuc, M.C.; Banu, O.; Bezirtzoglou, E.; Lazar, V.; 2016. Rosmarinus officinalis essential oil and eucalyptol act as efflux pumps inhibitors and increase ciprofloxacin efficiency against Pseudomonas aeruginosa and Acinetobacter baumannii MDR strains. ROMANIAN BIOTECHNOLOGICAL LETTERS, 21, 11796-11804;
  10. Mihailescu, I.N.; Bociaga, D.; Socol, G.; Stan, G.E.; Chifiriuc, M.C.; Bleotu, C.; Husanu M.A.; Popescu-Pelin, G.; Duta, L.; Luculescu, C.R.; Negut, I.; Hapenciuc, C.; Besleaga, C.; Zgura, I.; Miculescu, F.; 2016. Fabrication of antimicrobial silver-doped carbon structures by combinatorial pulsed laser deposition. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 515, 592-606;
  11. Visan, A.; Stan, G.E.; Ristoscu, C.; Popescu-Pelin, G.; Sopronyi, M.; Besleaga, C.; Luculescu, C.; Chifiriuc, M.C.; Hussien M.D., Marsan O., Kergourlay E., Grossin D., Brouillet F., Mihailescu I.N. 2016. Combinatorial MAPLE deposition of antimicrobial orthopedic maps fabricated from chitosan and biomimetic apatite powders. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 511, 505-515;
  12. Radulescu, D.; Voicu, G.; Oprea, A.E.; Andronescu, E.; Grumezescu, V.; Holban, A.M.; Vasile, B.S.; Surdu, A.V.; Grumezescu, A.M.; Socol, G.; Mogoanta, L.; Mogosanu, G.D.; Balaure, P.C.; Radulescu, R.; Chifiriuc, M.C.; 2016. Mesoporous silica coatings for cephalosporin active release at the bone-implant interface. APPLIED SURFACE SCIENCE, 374, 165-171;
  13. Stan, M.S.; Nica, I.C.; Dinischiotu, A.; Varzaru, E.; Iordache, O.G.; Dumitrescu, I.; Popa, M.; Chifiriuc, M.C.; Pircalabioru, G.G.; Lazar, V.; Bezirtzoglou, E.; Feder, M.; Diamandescu, L.; 2016. Photocatalytic, antimicrobial and biocompatibility features of cotton knit coated with Fe-N-doped titanium dioxide nanoparticles. MATERIALS, 9, 1-15;
  14. Cristescu, R.; Visan, A.; Socol, G.; Surdu, A.V.; Oprea, A.E.; Grumezescu, A.M.; Chifiriuc, M.C.; Boehm, R.D.; Yamaleyeva, D.; Taylor, M.; Narayan, R.J.; Chrisey, D.B.; 2016. Antimicrobial activity of biopolymeric thin films containing flavonoid natural compounds and silver nanoparticles fabricated by MAPLE: A comparative study. APPLIED SURFACE SCIENCE, 374, 290-296
  15. Floroian, L.; Ristoscu, C.; Mihailescu, N.; Negut, I.; Badea, M.; Ursutiu, D.; Chifiriuc, M.C.; Urzica, I.; Dyia, H.M.; Bleotu, C.; Mihailescu, I.N.; 2016. Functionalized antimicrobial composite thin films printing for stainless steel implant coatings. MOLECULES, 21, 1-18;
  16. Oprea, A.E.; Pandel, L.M.; Dumitrescu, A.M.; Andronescu, E.; Grumezescu, V.; Chifiriuc, M.C.; Mogoanta, L.; Balseanu, T.A.; Mogosanu, G.D.; Socol, G.; Grumezescu, A.M.; Iordache, F.; Maniu, H.; Chirea, M.; Holban, A.M.; 2016. Bioactive ZnO coatings deposited by MAPLE - An appropriate strategy to produce efficient anti-biofilm surfaces. MOLECULES, 21, 1-11;
  17. Radulescu, M.; Andronescu, E.; Dolete, G.; Popescu, R.C.; Fufa, O.; Chifiriuc, M.C.; Mogoanta, L.; Balseanu, T.A.; Mogosanu, G.D.; Grumezescu, A.M.; Holban, A.M.; 2016. Silver nanocoatings for reducing the exogenous microbial colonization of wound dressings. MATERIALS, 9, 1-15;
  18. Radulescu, D.; Grumezescu, V.; Andronescu, E.; Holban, A.M.; Grumezescu, A.M.; Socol, G.; Oprea, A.E.; Radulescu, M.; Surdu, A.; Trusca, R.; Radulescu, R.; Chifiriuc, M.C.; Stan, M.S.; Constanda, S.; Dinischiotu, A.; 2016. Biocompatible cephalosporin-hydroxyapatite-poly(lactic-co-glycolic acid)-coatings fabricated by MAPLE technique for the prevention of bone implant associated infections. APPLIED SURFACE SCIENCE, 374, 387-396;
  19. Radulescu, M.; Andronescu, E.; Cirja, A.; Holban, A.M.; Mogoanta, L.; Balseanu, T.A.; Catalin, B.; Neagu, T.P.; Lascar, I.; Florea, D.A.; Grumezescu, A.M.; Ciubuca, B.; Lazar, V.; Chifiriuc, M.C.; Bolocan, A.; 2016. Antimicrobial coatings based on zinc oxide and orange oil for improved bioactive wound dressings and other applications. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY, 57, 107-114;
  20. Stan, M.S.; Constanda, S.; Grumezescu, V.; Andronescu, E.; Ene, A.M.; Holban, A.M.; Vasile, B.S.; Mogoanta, L.; Balseanu, T.A.; Mogosanu, G.D.; Socol, G.; Grumezescu, A.M.; Dinischiotu, A.; Lazar, V.; Chifiriuc, M.C.; 2016. Thin coatings based on ZnO@C18-usnic acid nanoparticles prepared by MAPLE inhibit the development of Salmonella enterica early biofilm growth. APPLIED SURFACE SCIENCE, 374, 318-325;
  21. Cristescu, R.; Visan, A.; Socol, G.; Surdu, A.V.; Oprea, A.E.; Grumezescu, A.M.; Chifiriuc, M.C.; Boehm, R.D.; Yamaleyeva, D.; Taylord, M.; Narayan, R.J.; Chriseye, D.B.; 2016. Antimicrobial activity of biopolymeric thin films containing flavonoid natural compounds and silver nanoparticles fabricated by MAPLE: A comparative study. APPLIED SURFACE SCIENCE, 374, 290-296;
  22. Croitoru, C.D.; Mihaiescu, D.E.; Chifiriuc, M.C.; Bolocan, A.; Bleotu, C.; Grumezescu, A.M.; Saviuc, C.M.; Lazar, V.; Curuţiu, C.; 2015. Efficiency of gentamicin loaded in bacterial polysaccharides microcapsules against intracellular gram-positive and gram-negative invasive pathogens. ROMANIAN JOURNAL OF MORPHOLOGY AND EMBRYOLOGY, 56, 1417-1421;
  23. Mihai, M.M.; Holban, A.M.; Giurcaneanu, C.; Popa, L.G.; Oanea, R.M.; Lazar, V.; Chifiriuc, M.C.; Popa, M.; Popa, M.I.; 2015. Microbial biofilms: impact on the pathogenesis of periodontitis, cystic fibrosis, chronic wounds and medical device-related infections. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 15, 1552-1576;
  24. Grumezescu, V.; Andronescu, E.; Holban, A.M.; Socol, G.; Grumezescu, A.M.; Ficai, A.; Lazar, V.; Chifiriuc, M.C.; Trusca, R.; Iordache, F; 2015. Fabrication and characterization of functionalized surfaces with 3-amino propyltrimethoxysilane films for anti-infective therapy applications. APPLIED SURFACE SCIENCE, 336, 401-406;
  25. Popa, C.L.; Ciobanu, C.S.; Voicu, G.; Vasile, E.; Chifiriuc, M.C.; Iconaru, S.L.; Predoi, D.; 2015. Influence of Thermal Treatment on the Antimicrobial Activity of Silver-Doped Biological Apatite. NANOSCALE RESEARCH LETTERS, 10, 502-512;
  26. Grumezescu, V.; Andronescu, E.; Holban, A.M.; Mogoantă, L.; Mogoşanu, G.D.; Grumezescu, A.M.; Stanculescu, A.; Socol, G.; Iordache, F.; Maniu, H.; Chifiriuc, M.C.; 2015. MAPLE fabrication of thin films based on kanamycin functionalized magnetite nanoparticles with anti-pathogenic properties. APPLIED SURFACE SCIENCE, 336, 188-195;
  27. Stoica, P.; Rapa, M.; Chifiriuc, M.C.; Lungu, M.; Tatia, R.; Nita, M.I.; Grumezescu, A.M.; Bertesteanu, B.; Bezirtzoglou, E.; Lazar, V.; 2015. Antifungal bionanocomposites based on poly (lactic acid) and silver nanoparticles for potential medical devices. ROMANIAN BIOTECHNOLOGICAL LETTERS, 20, 10696-10707;
  28. Chifiriuc, C.M.; Grumezescu, A.M.; 2015. Nanobioactive structures for drug targeting and delivery. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 15, 1423;
  29. Chifiriuc, C.M.; Grumezescu, A.M.; 2015. Editorial: micro and nanoscale materials for boosting the antimicrobial fight. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 15, 1551;
  30. Popa, M.; Hussien, M.D.; Cirstea, A.; Grigore, R.; Lazar, V.; Bezirtzoglou, E.; Chifiriuc, M.C.; Sakizlian, M.; Stavropoulou, E.; Bertesteanu, S.; 2015. Insights on metal based dental implants and their interaction with the surrounding. CURRENT TOPICS IN MEDICAL CHEMISTRY, 15, 1614-1621;
  31. Pop, C.S.; Hussien, M.D.; Popa, M.; Mares, A.; Grumezescu, A.M.; Grigore, R.; Lazar, V.; Chifiriuc, M.C.; Sakizlian, M.; Bezirtzoglou, E.; Bertesteanu, S.; 2015. Metallic-based micro and nanostructures with antimicrobial activity. CURRENT TOPICS IN MEDICAL CHEMISTRY, 15, 1577-1582;
  32. Grumezescu, A.M.; Ghitulica, C.D.; Voicu, G.; Huang, K.S.; Yang, C.H.; Ficai, A.; Vasile, B.S.; Grumezescu, V.; Bleotu, C.; Chifiriuc, M.C.; 2014. Anionic polymers and 10 nm Fe₃O₄@UA wound dressings support human foetal stem cells normal development and exhibit great antimicrobial properties. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 463, 146-154;
  33. Grumezescu, V.; Holban, A.M.; Grumezescu, A.M.; Socol, G.; Ficai, A.; Vasile, B.S; Truscă, R.; Bleotu; C.; Lazar, V.; Chifiriuc, C.M.; Mogosanu, G.D.; 2014. Usnic acid-loaded biocompatible magnetic PLGA-PVA microsphere thin films fabricated by MAPLE with increased resistance to staphylococcal colonization. BIOFABRICATION, 6, 1-12;
  34. Limban, C.; Missir, A.V.; Grumezescu, A.M.; Oprea, A.E.; Grumezescu, V.; Vasile, B.S.; Socol, G.; Trusca, R.; Caproiu, M.T.; Chifiriuc, M.C.; Galateanu, B.; Costache, M.; Morusciag, L.; Pircalabioru, G.; Nuta, D.C.; 2014. Bioevaluation of Novel Anti-Biofilm Coatings Based on PVP/Fe3O4 Nanostructures and 2-((4-Ethylphenoxy) methyl)-N-(arylcarbamothioyl)benzamides. MOLECULES, 19, 12011-12030;
  35. Bertesteanu, S.; Chifiriuc, M.C.; Grumezescu, A.M.; Printza, A.G.; Marie-Paule, T.; Grumezescu, V.; Vlad, M.; Lazar, V.; Grigore, R.; 2014. Biomedical applications of synthetic, biodegradable polymers for the development of anti-infective strategies. CURRENT MEDICINAL CHEMISTRY, 21, 3383-3390;
  36. Grumezescu, V.; Socol, G.; Grumezescu, A.M.; Holban, A.M.; Ficai, A.; Trusca, R.; Bleotu, C.; Balaure, P.C.; Cristescu, R.; Chifiriuc, M.C.; 2014. Functionalized antibiofilm thin coatings based on PLA-PVA microspheres loaded with usnic acid natural compounds fabricated by MAPLE. APPLIED SURFACE SCIENCE, 302, 262-267;
  37. Mogosanu, G.D.; Grumezescu, A.M.; Chifiriuc, M.C.; 2014. Keratin-based biomaterials for biomedical applications. CURRENT DRUG TARGETS, 15, 518-530;
  38. Bertesteanu, S.; Triaridis, S.; Stankovic, M.; Lazar, V.; Chifiriuc, M.C.; Vlad, M.; Grigore, R.; 2014. Polymicrobial wound infections: Pathophysiology and current therapeutic approaches. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 463, 119-126;
  39. Grumezescu, A.M.; Ghitulica, C.D.; Voicu, G.; Huang, K.S.; Yang, C.H.; Ficai, A.; Vasile, B.S.; Grumezescu, V.; Bleotu, C.; Chifiriuc, M.C.; 2014. New silica nanostructure for the improved delivery of topical antibiotics used in the treatment of staphylococcal cutaneous infections. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 463, 170-176;
  40. Chifiriuc, M.C.; Grumezescu, A.M.; Grumezescu, V.; Bezirtzoglou, E.; Lazar, V.; Bolocan, A.; 2014. Biomedical applications of natural polymers for drug delivery. CURRENT ORGANIC CHEMISTRY, 18, 152-164;
  41. Grumezescu, A.M.; Chifiriuc. C.M.; 2014. Prevention of microbial biofilms - The contribution of micro and nanostructured materials. CURRENT MEDICINAL CHEMISTRY, 21, 3311;
  42. Vlad, M.; Andronescu, E.; Grumezescu, A.M.; Ficai, A.; Voicu, G.; Bleotu, C.; Chifiriuc, M.C.; 2014. Carboxymethyl-cellulose/Fe3O4 nanostructures for antimicrobial substances delivery. BIO-MEDICAL MATERIALS AND ENGINEERING, 24, 1639-1646;
  43. Limban, C.; Grumezescu, M.A.; Chirea, M.; Matei, L.; Chifiriuc, M.C.; 2013. Antimicrobial potential of benzamides and derived nanosystems for controlling in vitro biofilm development on medical devices. CURRENT ORGANIC CHEMISTRY, 17, 162-175;
  44. Lungu, M.; Gavriliu, S.; Enescu, E.; Ion, I.; Bratulescu, A.; Mihaescu, G.; Marutescu, L.; Chifiriuc, M.C.; 2013. Silver-titanium dioxide nanocomposites as effective antimicrobial and antibiofilm agents. JOURNAL OF NANOPARTICLE RESEARCH, 16, 1-15;
  45. Chifiriuc, M.C.; Grumezescu, A.M.; Saviuc, C.; Hristu, R.; Grumezescu, V.; Bleotu, C.; Stanciu, G.; Mihaiescu, D.E.; Andronescu, E.; Lazar, V.; Radulescu, R.; 2013. Magnetic nanoparticles for controlling in vitro fungal biofilms. CURRENT ORGANIC CHEMISTRY, 17, 1023-1028;
  46. Curutiu, C.; Chifiriuc, M.C.; Mitache, M.; 2013. Pseudomonas aeruginosa-Eukaryotic cell crosstalk: mediators, mechanisms and Implications for the antimicrobial therapy. CURRENT ORGANIC CHEMISTRY, 17, 149-154;
  47. Prodan, A.M.; Iconaru. S.L.; Ciobanu. C.S.; Chifiriuc. M.C.; Stoicea. M.; Predoi, D.; 2013. Iron Oxide Magnetic Nanoparticles: Characterization and Toxicity Evaluation by In Vitro and In Vivo Assays. JOURNAL OF NANOMATERIALS, 2013, 1-10;
  48. Costescu, A.; Ciobanu, C.S.; Iconaru, S.L.; Ghita, R.V.; Chifiriuc, C.M.; Marutescu, L.G.; Predoi, D.; 2013. Fabrication, Characterization, and Antimicrobial Activity, Evaluation of Low Silver Concentrations in Silver-Doped Hydroxyapatite Nanoparticles. JOURNAL OF NANOMATERIALS, 2013, 1- 9;
  49. Mihaiescu, D.E.; Cristescu, R.; Dorcioman, G.; Popescu, C.E.; Nita, C.; Socol, G.; Mihailescu, N.I.; Grumezescu, A.M.; Tamas, D.; Enculescu, M.; Negrea, R.F.; Ghica, C.; Chifiriuc, M.C.; Bleotu, C.; Chrisey, D.B.; 2013. Functionalized magnetite silica thin films fabricated by MAPLE with antibiofilm properties. BIOFABRICATION, 5, 1088-1758;
  50. Ciobanu, C.S.; Iconaru, S.L.; Chifiriuc, M.C.; Costescu, A.; Le Coustumer, P.; Predoi, D.; 2013. Synthesis and Antimicrobial Activity of Silver-Doped Hydroxyapatite Nanoparticles. BIOMED RESEARCH INTERNATIONAL, 2013, 1-10;
  51. Balaure, P.C.; Andronescu, E.; Grumezescu, A.M.; Ficai, A.; Huang, K.S.; Yang, C.H.; Chifiriuc, C.M.; Lin, Y.S.; 2012. Fabrication, characterization and in vitro profile based interaction with eukaryotic and prokaryotic cells of alginate-chitosan-silica biocomposite. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 441, 555-561;
  52. Cristescu, R.; Popescu, C.; Socol, G.; Iordache, I.; Mihailescu, I.N.; Mihaiescu, D.E.; Grumezescu, A.M.; Andronie, A.; Stamatin, I.; Chifiriuc, M.C.; Bleotu, C.; Saviuc, C.; Popa, M.; Chrisey, D.B.; 2012. Magnetic core/shell nanoparticle thin films deposited by maple: Investigation by chemical, morphological and in vitro biological assays. APPLIED SURFACE SCIENCE, 258, 9250-9255;
  53. Nitulescu, G.M.; Draghici, C.; Chifiriuc, M.C.; Marutescu, L.; Bleotu, C.; Missir, A.V.; 2012. Synthesis and antimicrobial screening of N-(1-methyl-1Hpyrazole-4-carbonyl)-thiourea derivatives. MEDICINAL CHEMISTRY RESEARCH, 21, 308-314;
  54. Chifiriuc, M.C.; Grumezescu, A.M.; Saviuc, C.; Croitoru, C.; Mihaiescu, D.E.; Lazar, V.; 2012. Improved antibacterial activity of cephalosporins loaded in magnetic chitosan microspheres. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 436, 201-205;
  55. Chifiriuc, M.C.; Grumezescu, V.; Grumezescu, A.M.; Saviuc, C.M.; Lazar, V.; Andronescu, E.; 2012. Hybrid magnetite nanoparticles/Rosmarinus officinalis essential oil nanobiosystem with antibiofilm activity. NANOSCALE RESEARCH LETTERS, 7, 1-7;
  56. Grumezescu, A.M.; Andronescu, E.; Ficai, A.; Bleotu, C.; Mihaiescu, D.E.; Chifiriuc, M.C.; 2012. Synthesis, characterization and in vitro assessment of the magnetic chitosan–carboxymethylcellulose biocomposite interactions with the prokaryotic and eukaryotic cells. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 436, 771–777;
  57. Anghel, I.; Holban, A.M.; Grumezescu, A.M.; Andronescu, E.; Ficai, A.; Anghel, A.G.; Maganu, M.; Lazar, V.; Chifiriuc, M.C.; 2012. Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development. NANOSCALE RESEARCH LETTERS, 7, 1-8;
  58. Limban, C.; Marutescu, L.; Chifiriuc, M.C.; 2011. Synthesis, spectroscopic properties and antipathogenic activity of new thiourea derivatives. MOLECULES, 16, 7593-7607;
  59. Limban, C.; Chifiriuc, M.C.; 2011. Antibacterial activity of new dibenzoxepinone oximes with fluorine and trifluoromethyl group substituents. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 12, 6432-6444.

Cărți / capitole de carte (selecție):

  1. Georgescu, M.; Chifiriuc, M.C.; Marinas, O.; Popa, M.; Stan, T.; Bertesteanu, S.V.; Lazar, V.; 2016. Natural compounds for wound healing, Chapter 4 in Worldwide Wound healing - Innovation in natural and conventional methods, Fonseca, C.J.V. (Ed.), Intech, 61-89, ISBN 978-953-51-4903-3;
  2. Chifiriuc, M.C.; Ficai, A.; Grumezescu, A.M.; Ditu, L.M.; Popa, M.; Iordache, C.; Holban, A.M.; Bertesteanu, S.F.V.; Grigore, R.; Lazar, V.; 2016. Soft tissue engineering and microbial infections: challenges and perspectives, Chapter 1 in Applications of nanobiomaterials – Vol. 5: Nanobiomaterials in soft tissue engineering, Grumezescu, A.M. (Ed.), Elsevier, 1-29, ISBN: 978-0-323-42865-1;
  3. Chifiriuc, M.C.; Grumezescu, A.M.; Ficai, A.; Holban, A.M.; 2014. Applications of nanotechnology for the development of new microbicidal and microbiostatic strategies, Chapter in Recent Developments in Biotechnology – Vol. 10: Nano-Biotechnology, Kumar, A. (Ed), Studium Press LLC, 473-502, ISBN: 1-62699-025-5;
  4. Grumezescu, A.M.; Holban, A.M.; Ficai, A.; Grumezescu, V.; Lazar, V.; Chifiriuc, M.C.; 2014. Nanosized materials with antibiofilm activity Chapter in Recent Developments in Biotechnology – Vol. 10: Nano-Biotechnology, Kumar, A. (Ed), Studium Press LLC, 263-284, ISBN: 1-62699-025-5.
  5. Mogosanu, G.D.; Grumezescu, A.M.; Balaure, P.C.; Chifiriuc, M.C.; 2013. Lavender oil: Composition and pharmacological actions, Chapter 7 in Recent progress in medicinal plants – Vol. 36: Essential Oils I, Govil, J.N.; Bhattacharya, S.; (Eds.), Studium Press LLC, 141-180; ISBN: 1-933699-96-5.
  6. Andronescu, E.; Grumezescu, A.M.; Ghitulica, C.; Ficai, A.; Ficai, D.; Chifiriuc, M.C.; 2012. Novel approach to fabricate magnetic nanostructures for biomedical applications Chapter in Nanotechnology Diagnostics and Therapeutics – Vol. VII, Navani, N.K.; Sinha, S.; (Eds), Studium Press LLC, 51-88, ISBN 1-62699-000-7;
  7. Lazar, V.; Chifiriuc, M.C.; 2011. Mechanisms and experimental models for the assessment of biofilms phenotypic resistance/tolerance, Chapter in Science against microbial pathogens: communicating current research and technological advances, Méndez-Vilas, A. (Ed), Formatex Research Center, 906-911, ISBN 13: 978-84-939843-1-1.

Brevete de invenție (selecție):

  1. Limban, C.; Missir, A.; Chirita, I.C.; Draghici, B.; Chifiriuc, M.C.; Bleotu, C.; RO122638 (B1) / 2007. Tioureide -N,N’-disubstituite ale acidului 2-(4-fluorofenoximetil)-benzoic și procedeu de preparare a acestora / -N,N’-Disubstituted Thioureides Of 2-(4-Fluorophenoxymethyl)-Benzoic Acid Used As An Anti-Microbial Agent;
  2. Stecoza, C.E.; Chirita, I.C.; Caproiu, M.T.; Draghici, C.; Chifiriuc, M.C.; Ilie, C.; RO123114 / 2009. Derivați de 6,11-dihidrodibrnzo (b,e) tiepin-5,5-dioxid, procedeu de preparare a acestora, compoziție farmaceutică ce îi conține și utilizarea lor ca agenți antimicrobieni / 6,11-Dihydrodibenzo(b,e)thiepine-5,5-dioxide derivatives, process for preparing the same, pharmaceutical composition containing the same and utilization there of as antimicrobial agents;
  3. Moldovan, L.; Alexandru, V.; Craciunescu, O.; Lazar, V.; Balotescu, C.; RO122181 (B1) / 2009. Hidrogel din componente naturale pentru regenerarea țesutului dermic lezat / Natural hydrogel for the regeneration of injured dermal tissue;
  4. Lazar, V.; Chifiriuc, M.C.; Cernat, R.; Bulai, D.; RO123145 / 2007. Method for assessment of the bacterial biofilms to antimicrobial substances;
  5. Lazar, V.; Chifiriuc, M.C.; Cernat, R.; Bulai, D.; RO23146 / 2007. Antibiotic susceptibility method for testing the microbial biofilms.

Proiecte internaționale (selecție):

  1. M-ERA.NET / 2017-2020. Advanced biodegradable materials based on MgB2 resistant to microbial colonization (BIOMB);
  2. JPI-EC-AMR Joint Transnational Call for Proposals / 2016. Transmission dynamics of antimicrobial resistance – Antibiotic resistance in wastewater: Transmission risks for employees and residents around waste water treatment plants (AWARE-WWTP);
  3. PHARE 115101 / 2002-2006. Strengthening the institutional and administrative capacity of the MoHF to adopt and implement the Acquis Communautaire in the field of water and related risks project;
  4. EARS-Net / 2001-2009. European Antimicrobial Resistance Surveillance System (EARSS).

Proiecte naționale (selecție):

  1. BG 116 / 2016-2018. Transferul cunoașterii privind investigarea proprietăţilor antiinfecţioase şi antitumorale ale unor noi formulări cosmetice și farmaceutice pe bază de extracte naturale / Knowledge Transfer on investigation of the anti-infective and antitumoral activity of novel cosmetic and pharmaceutical formulations based on natural extracts (BeeHerE);
  2. PCE-1176 / 2016-2018. Metodă rapidă bazată pe citometria în flux pentru detectarea microorganismelor și testare a sensibilității la antibiotice direct din produsele patologice;
  3. PCCA 215 / 2014-2016. Materiale şi acoperiri nanostructurate inovative cu activitate antimicrobiană pentru aplicaţii medicale / Innovative nanostructured materials and coatings with antimicrobial activity for medical applications (INMATCO);
  4. TE 373 / 2015-2017. Evaluarea riscului de transfer al unor gene pentru carbapenemaze prin intermediul transpozonilor / Risk assessment of transposon-mediated transfer of some carbapenemase gene;
  5. C 59 / 2014. Romanian Biotechnological Letters (Subvenție);
  6. IDEI 154 / 2011-2014. Efectele moleculelor de quorum sensing produse de P. aeruginosa asupra genomului de Drosophila: o noua cale de identificare a genelor candidat implicate in comunicarea gazda-agent infectios / Effects of P. aeruginosa quorum sensing molecules on Drosophila genome: a new tool to identifycandidate genes involved in host-pathogen crosstalk;
  7. TE 135 / 2010-2013. Profiluri de virulență și antibiorezistența specifice infecțiilor nosocomiale produse de tulpini de Staphylococcus aureus și Pseudomonas aeruginosa;
  8. CNCSIS 187 / 2007-2008. Rolul feromonilor bacterieni produși de Pseudomonas aeruginosa în medierea interacțiunilor dintre celulele bacteriene și celule gazdei eucariote în cursul procesului infecțios;
  9. CEEX_MII 1640 / 2005-2008. Aplicații ale mecanismelor de QS în dezvoltarea unor noi strategii anti-infecțioase.